Invention Grant
US07888505B2 6,7-dihydrobenzimidazo[1,2-c]quinazolin-6-one carboxylic acids, their esters, and methods of synthesis thereof
有权
6,7-二氢苯并咪唑并[1,2-c]喹唑啉-6-酮羧酸,它们的酯及其合成方法
- Patent Title: 6,7-dihydrobenzimidazo[1,2-c]quinazolin-6-one carboxylic acids, their esters, and methods of synthesis thereof
- Patent Title (中): 6,7-二氢苯并咪唑并[1,2-c]喹唑啉-6-酮羧酸,它们的酯及其合成方法
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Application No.: US12160410Application Date: 2007-01-15
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Publication No.: US07888505B2Publication Date: 2011-02-15
- Inventor: Tatyana Doutova , Pavel I. Lazarev , Elena N. Sidorenko , Valery S. Kuzmin
- Applicant: Tatyana Doutova , Pavel I. Lazarev , Elena N. Sidorenko , Valery S. Kuzmin
- Applicant Address: JP Tokyo
- Assignee: Crysoptix, KK
- Current Assignee: Crysoptix, KK
- Current Assignee Address: JP Tokyo
- Agency: Houst Consulting
- Priority: GB0600763.7 20060113
- International Application: PCT/GB2007/000102 WO 20070115
- International Announcement: WO2007/080420 WO 20070719
- Main IPC: C07D471/00
- IPC: C07D471/00 ; C07D487/00 ; C07D491/00
![6,7-dihydrobenzimidazo[1,2-c]quinazolin-6-one carboxylic acids, their esters, and methods of synthesis thereof](/abs-image/US/2011/02/15/US07888505B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to a 6,7-dihydrobenzimidazo[1,2-c]quinazolin-6-one carboxylic acid and its esters of the general structural formula (I), and provides a method for their synthesis (I) where R and each R′ are selected independently from the list comprising —H—CH3, —C2H5, —C3H7, -iso-C3H7, —CH2CH2CH2CH3, —CH(CH3)CH2CH3, —CH2CH(CH3)CH3 and —C(CH3)3; n is 1, 2, 3 or 4; Y is a substituent selected from the list comprising —CH3, —C2H5, —NO2, —Cl, —Br, —F, —CF3, —CN, —OH, —OCH3, —OC2H5, —OCOCH3, —OCN, —SCN, —NH2, —NHCOCH3; and z is 0, 1, 2, 3 or 4.
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