The present invention provides a power-saving laser pointer mouse including a battery, a micro-controller and a laser diode. The power-saving laser pointer mouse can be operated in multi-stage power-saving modes according to the voltage value of the battery. The lighting time interval of the laser diode is adjusted by the micro-controller according to the voltage value of the battery. When the voltage value of the battery is reduced, the lighting time interval of the laser diode is shortened so as to achieve the power-saving purpose.