A system supports creation and modification of a flexible and comprehensive location structure model able to track patients in a healthcare (or other) setting and identify suitable patient locations and location availability via a user friendly display interface. A method processes location related information for use in facilitating movement of a patient in a healthcare enterprise. The method involves establishing a profile comprising information identifying multiple locations available to accommodate a patient for different purposes. The profile incorporates attributes including a location type identifier, and a location characteristic of clinical significance influencing availability of a particular location to a patient having a particular medical condition. The profile is employed in providing a user with an indication of location availability in response to user command.