Systems and processes are provided for safely facilitating transfer of down-hole devices through an adaptive seal assembly capping a well under pressure. At least one dynamic seal is provided having a size and shape to accommodate varying cross section of an elongated down-hole device, such as a logging tool. The adaptive seal assembly includes a mating flange for coupling its open end to a reversibly sealable wellhead fixture. A pressure is maintained along a wellbore side of the reversible seal, while the aperture is varied according to the varying cross section of the down-hole device as it is translated along the axis. More than one dynamic seals can be actuated in a controlled sequence to apply axial thrust in a preferred direction to the tool. One or more robotic systems can be provided to further expedite manipulation of at least one of the tool and the vessel.