A system for removal of H2S from sulfur-containing reformate comprising a permanent canister assembly having fittings for flow of reformate therethrough and a replaceable cartridge assembly containing an H2S adsorber element and fittings for convenient, simple, and reliable mating and sealing with the permanent canister assembly. The cartridge assembly comprises a housing that may be optionally a full cylinder or a semi-cylinder. The cartridge assembly may be easily reloaded off-line for re-use of the cartridge components with a fresh adsorber element. Preferably, the adsorber element is also renewable off-line for re-use.