Invention Grant
- Patent Title: Viral chemokine-antigen fusion proteins
- Patent Title (中): 病毒趋化因子 - 抗原融合蛋白
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Application No.: US10380927Application Date: 2001-09-17
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Publication No.: US07897152B2Publication Date: 2011-03-01
- Inventor: Larry W. Kwak , Arya Biragyn
- Applicant: Larry W. Kwak , Arya Biragyn
- Applicant Address: US DC Washington
- Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
- Current Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
- Current Assignee Address: US DC Washington
- Agency: Klarquist Sparkman, LLP
- International Application: PCT/US01/29075 WO 20010917
- International Announcement: WO02/22687 WO 20020321
- Main IPC: A61K39/12
- IPC: A61K39/12 ; A61K38/00 ; A61K45/00 ; C08H1/00 ; A61K39/00 ; A61K31/00
Abstract:
The present invention relates to a vaccine for increasing the immunogenicity of a tumor antigen thus allowing treatment of cancer, as well as a vaccine that increases the immunogenicity of a viral antigen, thus allowing treatment of viral infection, including immunodeficiency virus (HIV) infection. In particular, the present invention provides a fusion protein comprising a viral chemokine fused to either a tumor antigen or viral antigen which is administered as either a protein or nucleic acid vaccine to elicit an immune response effective in treating cancer or effective in treating or preventing viral infection.
Public/Granted literature
- US20040110165A1 Viral chemokine-antigen fusion proteins Public/Granted day:2004-06-10
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