Invention Grant
- Patent Title: Bone graft and scaffolding materials immobilized with osteogenesis enhancing peptides on the surface
- Patent Title (中): 骨移植物和脚手架材料固定在骨形成增强肽表面
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Application No.: US10593430Application Date: 2005-03-18
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Publication No.: US07897163B2Publication Date: 2011-03-01
- Inventor: Yoon Jeong Park , Chong-Pyoung Chung , Seung Jin Lee , Sang Hoon Rhee
- Applicant: Yoon Jeong Park , Chong-Pyoung Chung , Seung Jin Lee , Sang Hoon Rhee
- Applicant Address: KR
- Assignee: Seoul National University Industry Foundation
- Current Assignee: Seoul National University Industry Foundation
- Current Assignee Address: KR
- Agency: Intellectual Property/Technology Law
- Agent Kelly K. Reynolds; Steven J. Hultquist
- Priority: KR10-2004-0019010 20040319
- International Application: PCT/KR2005/000801 WO 20050318
- International Announcement: WO2005/089826 WO 20050929
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/04 ; A61K38/16 ; A61K38/17 ; A61K38/18

Abstract:
The present invention relates to a bone graft material and a scaffold for tissue engineering applications, which have an osteogenesis-promoting peptide immobilized on the surface. More particularly, the invention relates to a bone graft material and a scaffold for tissue engineering applications, which have a cell adhesion-inducing peptide and/or tissue growth factor-derived peptide immobilized on the surface. By the osteogenesis-promoting peptide immobilized on the surface, the inventive bone graft material and scaffold for tissue engineering applications can promote the transition, proliferation and differentiation of cells associated with regeneration, and eventually maximize the regeneration of tissue. Moreover, the peptide immobilized on the surface has low molecular weight, indicating a reduced risk of immune responses upon its application in the body, and can be present in a stable form within the body, thus showing lasting effects. Accordingly, the peptide makes it expedient to perform surgical operations for the regeneration of periodontal tissue, alveolar bone and other bone tissues, and will show high therapeutic effect.
Public/Granted literature
- US20070160681A1 Bone graft and scaffolding materials immobilized with osteogenesis enhancing peptides on the surface Public/Granted day:2007-07-12
Information query
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