Invention Grant
US07897332B2 Methods for the detection of HIV-1 or -2 antigens employing monoclonal antibodies that recognize a shared HIV-1/-2 epitope in the capsid p24/p26 proteins
有权
使用识别衣壳p24 / p26蛋白中共享的HIV-1 / -2表位的单克隆抗体检测HIV-1或-2抗原的方法
- Patent Title: Methods for the detection of HIV-1 or -2 antigens employing monoclonal antibodies that recognize a shared HIV-1/-2 epitope in the capsid p24/p26 proteins
- Patent Title (中): 使用识别衣壳p24 / p26蛋白中共享的HIV-1 / -2表位的单克隆抗体检测HIV-1或-2抗原的方法
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Application No.: US10714689Application Date: 2003-11-17
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Publication No.: US07897332B2Publication Date: 2011-03-01
- Inventor: Sheng C. Lou , Jeffrey C. Hunt , John G. Konrath , Xiaoxing Qiu , James W. Scheffel , Joan D. Tyner
- Applicant: Sheng C. Lou , Jeffrey C. Hunt , John G. Konrath , Xiaoxing Qiu , James W. Scheffel , Joan D. Tyner
- Applicant Address: US IL Abbott Park
- Assignee: Abbott Laboratories
- Current Assignee: Abbott Laboratories
- Current Assignee Address: US IL Abbott Park
- Agency: Larcher & Chao Law Group
- Agent Audrey L. Bartnicki; Carol Larcher
- Main IPC: C12Q1/70
- IPC: C12Q1/70 ; G01N33/53 ; A61K39/42
Abstract:
The present invention relates to novel monoclonal antibodies which may be used in the detection of Human Immunodeficiency Virus (HIV). These antibodies exhibit an unusually high degree of sensitivity, a remarkably broad range of specificity, and bind to novel shared, non-cross-reactive epitopes. In particular, the monoclonal antibodies of the present invention may be utilized to detect HIV-1 antigen and HIV-2 core antigen in a patient sample.
Public/Granted literature
- US20040101831A1 Monoclonal antibodies to human immunodeficiency virus and uses thereof Public/Granted day:2004-05-27
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