Invention Grant
- Patent Title: Methods for the detection, analysis and isolation of nascent proteins
- Patent Title (中): 新生蛋白的检测,分析和分离方法
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Application No.: US10174368Application Date: 2002-06-18
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Publication No.: US07897335B2Publication Date: 2011-03-01
- Inventor: Kenneth J. Rothschild , Sadanand Gite , Jerzy Olejnik
- Applicant: Kenneth J. Rothschild , Sadanand Gite , Jerzy Olejnik
- Applicant Address: US MA Waltham
- Assignee: Ambergen, Inc.
- Current Assignee: Ambergen, Inc.
- Current Assignee Address: US MA Waltham
- Agency: Medlen + Carroll, LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68

Abstract:
This invention relates to non-radioactive markers that facilitate the detection and analysis of nascent proteins translated within cellular or cell-free translation systems. Nascent proteins containing these markers can be rapidly and efficiently detected, isolated and analyzed without the handling and disposal problems associated with radioactive reagents. Preferred markers are dipyrrometheneboron difluoride (4,4-difluoro-4-bora-3a,4a-diaza-s-indacene) dyes.
Public/Granted literature
- US20030092031A1 Methods for the detection, analysis and isolation of nascent proteins Public/Granted day:2003-05-15
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