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US07897348B2 Detection of negatively charged polymers using water-soluble, cationic, polythiophene derivatives 失效
使用水溶性阳离子聚噻吩衍生物检测带负电荷的聚合物

Detection of negatively charged polymers using water-soluble, cationic, polythiophene derivatives
Abstract:
Novel methods allowing for the simple optical and electrochemical detection of double-stranded oligonucleotides are disclosed. The methods are rapid, selective and versatile. Advantageously, they do not require any chemical reaction on the probes or on the analytes since they are based on different electrostatic interactions between cationic poly(3-alkoxy-4-methylthiophene) derivatives and single-stranded or double-stranded (hybridized) oligonucleotides.
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