Invention Grant
US07897348B2 Detection of negatively charged polymers using water-soluble, cationic, polythiophene derivatives
失效
使用水溶性阳离子聚噻吩衍生物检测带负电荷的聚合物
- Patent Title: Detection of negatively charged polymers using water-soluble, cationic, polythiophene derivatives
- Patent Title (中): 使用水溶性阳离子聚噻吩衍生物检测带负电荷的聚合物
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Application No.: US12838337Application Date: 2010-07-16
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Publication No.: US07897348B2Publication Date: 2011-03-01
- Inventor: Mario Leclerc , Hoang Anh Ho , Maurice Boissinot
- Applicant: Mario Leclerc , Hoang Anh Ho , Maurice Boissinot
- Applicant Address: CA
- Assignee: Geneohm Sciences Canada, Inc.
- Current Assignee: Geneohm Sciences Canada, Inc.
- Current Assignee Address: CA
- Agency: Knobbe Martens Olson & Bear LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C07D333/32 ; C07D233/00 ; C07H21/02

Abstract:
Novel methods allowing for the simple optical and electrochemical detection of double-stranded oligonucleotides are disclosed. The methods are rapid, selective and versatile. Advantageously, they do not require any chemical reaction on the probes or on the analytes since they are based on different electrostatic interactions between cationic poly(3-alkoxy-4-methylthiophene) derivatives and single-stranded or double-stranded (hybridized) oligonucleotides.
Public/Granted literature
- US20100294723A1 DETECTION OF NEGATIVELY CHARGED POLYMERS USING WATER-SOLUBLE, CATIONIC, POLYTHIOPHENE DERIVATIVES Public/Granted day:2010-11-25
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