Invention Grant
US07897358B2 Canine transient receptor potential V2 (cTRPV2) and methods of screening for TRPV2 channel modulators
有权
犬瞬态受体电位V2（cTRPV2）和筛选TRPV2通道调节剂的方法
- Patent Title: Canine transient receptor potential V2 (cTRPV2) and methods of screening for TRPV2 channel modulators
- Patent Title (中): 犬瞬态受体电位V2（cTRPV2）和筛选TRPV2通道调节剂的方法
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Application No.: US12042016Application Date: 2008-03-04
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Publication No.: US07897358B2Publication Date: 2011-03-01
- Inventor: Ning Qin , Christopher M. Flores , Michael P. Neeper
- Applicant: Ning Qin , Christopher M. Flores , Michael P. Neeper
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica N.V.
- Current Assignee: Janssen Pharmaceutica N.V.
- Current Assignee Address: BE Beerse
- Agency: Patton Boggs, LLP
- Main IPC: C12N15/12
- IPC: C12N15/12 ; G01N33/567 ; C07K14/705
Abstract:
A recombinant canine TRPV2 channel which has been prepared by cDNA cloning and polymerase chain reaction techniques is disclosed. Expression systems for these channels and an assay using the expression systems are also disclosed. The recombinant TRPV2 channel can be used in assays to evaluate compounds which directly or indirectly interact with or bind to TRPV2 channel.
Public/Granted literature
- US20090165151A1 CANINE TRANSIENT RECEPTOR POTENTIAL V2 (CTRPV2) AND METHODS OF SCREENING FOR TRPV2 CHANNEL MODULATORS Public/Granted day:2009-06-25
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