Invention Grant
US07897383B2 Recombinant constructs and their use in reducing gene expression
有权
重组构建体及其在减少基因表达方面的应用
- Patent Title: Recombinant constructs and their use in reducing gene expression
- Patent Title (中): 重组构建体及其在减少基因表达方面的应用
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Application No.: US12256721Application Date: 2008-10-23
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Publication No.: US07897383B2Publication Date: 2011-03-01
- Inventor: Anthony J. Kinney , Kimberly F. Glassman , William James Gordon-Kamm , Keith S. Lowe , Scott E. Nichols , Kevin L. Stecca
- Applicant: Anthony J. Kinney , Kimberly F. Glassman , William James Gordon-Kamm , Keith S. Lowe , Scott E. Nichols , Kevin L. Stecca
- Applicant Address: US DE Wilmington US IA Johnston
- Assignee: E. I. du Pont de Nemours and Company,Pioneer Hi-Bred International
- Current Assignee: E. I. du Pont de Nemours and Company,Pioneer Hi-Bred International
- Current Assignee Address: US DE Wilmington US IA Johnston
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; C12Q1/68
Abstract:
Recombinant constructs useful for reducing the expression of endogenous mRNA and any substantially similar endogenous mRNA are disclosed. In particular, a recombinant construct comprising, inter alia, a suitable nucleic acid sequence and its reverse complement can be used to alter the expression of any homologous, endogenous RNA (i.e., the target RNA) which is in proximity to this suitable nucleic acid sequence.
Public/Granted literature
- US20090142829A1 Recombinant Constructs And Their Use In Reducing Gene Expression Public/Granted day:2009-06-04
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