Invention Grant
US07897574B2 Pharmaceutical composition for treating haemorrhagic shock and its consecutive symptoms
失效
用于治疗出血性休克及其连续症状的药物组合物
- Patent Title: Pharmaceutical composition for treating haemorrhagic shock and its consecutive symptoms
- Patent Title (中): 用于治疗出血性休克及其连续症状的药物组合物
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Application No.: US12158670Application Date: 2006-11-10
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Publication No.: US07897574B2Publication Date: 2011-03-01
- Inventor: Peter Petzelbauer , Rainer Henning
- Applicant: Peter Petzelbauer , Rainer Henning
- Applicant Address: US NJ Clinton
- Assignee: Ikaria Development Subsidiary Two LLC
- Current Assignee: Ikaria Development Subsidiary Two LLC
- Current Assignee Address: US NJ Clinton
- Agency: Hoffmann & Baron, LLP
- Priority: ATA2067/2005 20051223
- International Application: PCT/AT2006/000465 WO 20061110
- International Announcement: WO2007/070899 WO 20070628
- Main IPC: A61K38/36
- IPC: A61K38/36
Abstract:
The invention is concerned with the use of a peptide comprising the N-terminal sequence Gly-His-Arg-Pro-Leu-Asp-Lys-Lys-Arg-Glu-Glu-Ala-Pro-Ser-Leu-Arg-Pro-Ala- Pro-Pro-Pro-Ile-Ser-Gly-Gly-Gly-Tyr-Arg (SEQ ID NO: 1) or any allelic variant or derivative of said peptide possessing the biological property of matching the inducible VE-cadherin binding motif on the Bβ-chain (i.e. Bβ15-42) of human fibrin for the preparation of a pharmaceutical preparation for the treatment of shock, more specifically of hemorrhagic shock.
Public/Granted literature
- US20090005310A1 (En) Pharmaceutical Composition for Treating Haemorrhagic Shock and its Consecutive Symptoms Public/Granted day:2009-01-01
Information query
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