Invention Grant
US07897584B2 Taxanes covalently bounded to hyaluronic acid or hyaluronic acid derivatives
有权
紫杉烷共价结合透明质酸或透明质酸衍生物
- Patent Title: Taxanes covalently bounded to hyaluronic acid or hyaluronic acid derivatives
- Patent Title (中): 紫杉烷共价结合透明质酸或透明质酸衍生物
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Application No.: US10531853Application Date: 2003-10-10
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Publication No.: US07897584B2Publication Date: 2011-03-01
- Inventor: Gilda De Luca , Rinaldo Marini Bettolo , Luisa Maria Migneco
- Applicant: Gilda De Luca , Rinaldo Marini Bettolo , Luisa Maria Migneco
- Applicant Address: IT Abano Terme
- Assignee: Fidia Farmaceutici S.p.A.
- Current Assignee: Fidia Farmaceutici S.p.A.
- Current Assignee Address: IT Abano Terme
- Agency: Abelman, Frayne & Schwab
- Priority: ITPD2002A0271 20021018
- International Application: PCT/EP03/11239 WO 20031010
- International Announcement: WO2004/035629 WO 20040429
- Main IPC: A61K31/728
- IPC: A61K31/728 ; C08B37/00
Abstract:
The present invention relates to water-soluble taxanes covalently bounded to hyaluronic acid or hyaluronic acid derivatives, and in particular to paclitaxel and docetaxel, useful for the preparation of pharmaceutical compositions to be used in the field of oncology, in the treatment of autoimmune disorders and of restenoisis. The invention also relates to the process for preparing taxanes covalently bounded to hyaluronic acid or hyaluronic acid derivatives by direct synthesis between molecules of hyaluronic acid and of taxane or by indirect synthesis by the introduction of a spacer between the hyaluronic acid or hyaluronic acid derivative and the taxane.
Public/Granted literature
- US20060116346A1 Taxanes covalently bounded to hyaluronic acid or hyaluronic acid derivatives Public/Granted day:2006-06-01
Information query
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