Implantable devices for adhering eukaryotic cells and devices providing a substrate for eukaryotic cell growth and/or differentiation in vitro are described. Each device comprises a scaffold that is coated with a protein comprising an adhesive polypeptide that has at least 90% sequence identity to a specific peptide sequence within domain IV of perlecan. The devices adhere epithelial cells, epithelial stem cells, mesenchymal stem cells, and osteoblasts.