Invention Grant
- Patent Title: Urea derivatives of tropane, their preparation and their therapeutic application
- Patent Title (中): 托烷的尿素衍生物及其制备及其治疗应用
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Application No.: US12332547Application Date: 2008-12-11
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Publication No.: US07897773B2Publication Date: 2011-03-01
- Inventor: Michel Aletru , Alain Jean Braun , Claudie Namane , Olivier Venier , Christophe Philippo , Patrick Mougenot , Eric Nicolai , Stefan Gussregen
- Applicant: Michel Aletru , Alain Jean Braun , Claudie Namane , Olivier Venier , Christophe Philippo , Patrick Mougenot , Eric Nicolai , Stefan Gussregen
- Applicant Address: FR Paris
- Assignee: Sanofi-Aventis
- Current Assignee: Sanofi-Aventis
- Current Assignee Address: FR Paris
- Agent Jiang Lin
- Priority: FR0605785 20060627; FR0700507 20070125
- Main IPC: C07D401/00
- IPC: C07D401/00
Abstract:
The present invention is related to a compound of formula (I) wherein R1a, R1b, R1c, R1d, R2a, R2b, R3, R4, p, r and are as defined herein, its preparation, pharmaceutical composition and use as a modulator of the activity of the 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1).
Public/Granted literature
- US20090170894A1 UREA DERIVATIVES OF TROPANE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION Public/Granted day:2009-07-02
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