Invention Grant
US07897783B2 Intermediate compound for synthesis of viridiofungin a derivative
失效
用于合成维生素E衍生物的中间体化合物
- Patent Title: Intermediate compound for synthesis of viridiofungin a derivative
- Patent Title (中): 用于合成维生素E衍生物的中间体化合物
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Application No.: US11884556Application Date: 2006-02-16
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Publication No.: US07897783B2Publication Date: 2011-03-01
- Inventor: Tatsuya Kato , Nobuaki Kimura , Akemi Mizutani , Toshihiko Makino , Kenichi Kawasaki , Hiroshi Fukuda , Susumu Komiyama , Takuo Tsukuda
- Applicant: Tatsuya Kato , Nobuaki Kimura , Akemi Mizutani , Toshihiko Makino , Kenichi Kawasaki , Hiroshi Fukuda , Susumu Komiyama , Takuo Tsukuda
- Applicant Address: JP Tokyo
- Assignee: Chugai Seiyaku Kabushiki Kaisha
- Current Assignee: Chugai Seiyaku Kabushiki Kaisha
- Current Assignee Address: JP Tokyo
- Agency: Foley & Lardner LLP
- Priority: JP2005-041153 20050217
- International Application: PCT/JP2006/302687 WO 20060216
- International Announcement: WO2006/088071 WO 20060824
- Main IPC: C07D413/00
- IPC: C07D413/00
Abstract:
A method whereby a compound having HCV replication inhibitory activity and desired optical activity can be synthesized selectively and at high yield in a small number of steps by using a compound having a specific chiral auxiliary as a starting compound is provided.A compound represented by the formula (1-8): [wherein Y represents a group represented by the following formula: Q represents a protected carbonyl group; D represents —(CH2)m—R′, etc.; and n represents an integer of 0 to 10].
Public/Granted literature
- US20080293950A1 Production Process of Compound Having Anti-Hcv Action and Intermediate Thereof Public/Granted day:2008-11-27
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