A medical waste receptacle includes a housing shaped to define an interior cavity into which a waste collection bin is disposed. The housing is also shaped to include a slot in communication with the interior cavity, the slot being selectively enclosed by a disposal drawer adapted to pivot between closed and open positions. A movable latch selectively engages the drawer, the position of the latch being regulated by an electronic controller. In use, a barcode scanner in electrical connection with the controller retrieves an access code provided on a refuse container to be dispensed. If the access code is deemed valid, the controller disengages the latch from the drawer, thereby enabling the container to be dispensed into the bin through the slot. In the absence of receiving a valid access code, the controller retains the latch in engagement with the naturally closed disposal drawer, thereby precluding access to the bin.