An electrically-induced deflective amplification sensor as an actively controlled and reconfigurable nanomechanical sensor for the detection and recognition of chemicals, biomolecules, and gaseous molecules. The electrically-induced deflective amplification sensors use electric fields to control the bending of transducers, have adjustable sensitivities that depend on electric field strength, and reconfigurable operation ranges for the detection of target molecules at ultra-low and ultra-high concentrations. The sensors are highly integrated, sensitive, provide real-time detection ability, and do not require labels. The electrically-induced deflective amplification transducers can be reconfigured to identify molecules in spectroscopy. A new type of electrophoresis is established using nanostructured transducers. The E-IDEA is applicable to optical fiber, nanomechanical cantilever, waveguide and nanowire or nanotube tranducers. These adaptive and reconfigurable sensors have application in the fields of national security, public health and economic development.