An intramedullary nail and a targeting and/or nailing instrument includes a connector end which has an axially parallel projection which cooperates with an axially parallel recess on the hollow connection end of the nail. The engagement of the projection and recess fastens the nail under axial engagement on the connection end of the instrument in predefined rotational position on the instrument. A quick-fastener element engages in the connection end of the nail and has a first coupling element and the connection end of the nail has a second coupling element. The coupling elements are configured so that in a first rotational position relative to the axially parallel projection the instrument can be introduced into the connection end of the nail and in a second rotational position the coupling elements cooperate so that the nail is held axially fixedly on the instrument.