Invention Grant
US07901451B2 Drug-delivery endovascular stent and method for treating restenosis
有权
药物输送血管内支架和治疗再狭窄的方法
- Patent Title: Drug-delivery endovascular stent and method for treating restenosis
- Patent Title (中): 药物输送血管内支架和治疗再狭窄的方法
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Application No.: US11232598Application Date: 2005-09-22
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Publication No.: US07901451B2Publication Date: 2011-03-08
- Inventor: Douglas R. Savage , Ronald E. Betts , John E. Shulze
- Applicant: Douglas R. Savage , Ronald E. Betts , John E. Shulze
- Applicant Address: BM Hamilton
- Assignee: Biosensors International Group, Ltd.
- Current Assignee: Biosensors International Group, Ltd.
- Current Assignee Address: BM Hamilton
- Agency: Kilpatrick Townsend and Stockton LLP
- Main IPC: A61F2/82
- IPC: A61F2/82

Abstract:
A radially expandable, endovascular stent designed for placement at a site of vascular injury, for inhibiting restenosis at the site, a method of using, and a method of making the stent. The stent includes a radially expandable body formed of one or more metallic filaments and a liquid-infusible mechanical anchoring layer attached to or formed in outer surface of the filaments. A drug coating in the stent is composed of a substantially polymer-free composition of an anti-restenosis drug, and has a substratum infused in the anchoring layer and a substantially continuous surface stratum of drug that is brought into direct contact with the vessel walls at the vascular site. Thus, the rate of release of the anti-restenosis drug from the surface stratum into said vascular site is determined solely by the composition of said drug coating.
Public/Granted literature
- US20060069427A1 Drug-delivery endovascular stent and method for treating restenosis Public/Granted day:2006-03-30
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