Invention Grant
US07901669B2 Compositions for enhancing keratinocyte migration and epidermal repair via a receptor containing OSMRβ as a subunit, and applications thereof
有权
用于通过含有OSMR和bgr的受体增强角质形成细胞迁移和表皮修复的组合物 作为亚基，及其应用
- Patent Title: Compositions for enhancing keratinocyte migration and epidermal repair via a receptor containing OSMRβ as a subunit, and applications thereof
- Patent Title (中): 用于通过含有OSMR和bgr的受体增强角质形成细胞迁移和表皮修复的组合物 作为亚基，及其应用
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Application No.: US11721888Application Date: 2005-12-15
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Publication No.: US07901669B2Publication Date: 2011-03-08
- Inventor: Jean-Claude Lecron , Hughes Gascan , Franck Morel , Sylvie Chevalier , François-Xavier Bernard , Katia Boniface , Caroline Diveu
- Applicant: Jean-Claude Lecron , Hughes Gascan , Franck Morel , Sylvie Chevalier , François-Xavier Bernard , Katia Boniface , Caroline Diveu
- Applicant Address: FR Angers FR Poitiers Cedes FR Gencay
- Assignee: Universite d'Angers,Universite de Poitiers,Bioalternatives SAS
- Current Assignee: Universite d'Angers,Universite de Poitiers,Bioalternatives SAS
- Current Assignee Address: FR Angers FR Poitiers Cedes FR Gencay
- Agency: Alston & Bird LLP
- Priority: EP04293004 20041215
- International Application: PCT/EP2005/014199 WO 20051215
- International Announcement: WO2006/063865 WO 20060622
- Main IPC: A61K38/19
- IPC: A61K38/19 ; A61K38/20
Abstract:
The present invention relates to the field of epidermal repair. More particularly, the invention concerns the use of a molecule able to activate a heteromeric receptor comprising OSMRβ as a subunit, for the preparation of a composition for activating in vitro and/or in vivo keratinocyte migration and/or the expression of anti-microbial peptides by the keratinocytes. In particular, the invention concerns the use of OSM and/or IL-17 and/or TNFα and/or IL-31, or agonists thereof, for the preparation of cosmetic or dermatologic compositions.
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