Invention Grant
- Patent Title: Therapeutic retroviral vectors for gene therapy
- Patent Title (中): 用于基因治疗的治疗性逆转录病毒载体
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Application No.: US11150785Application Date: 2005-06-09
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Publication No.: US07901671B2Publication Date: 2011-03-08
- Inventor: Philippe Leboulch , Robert Pawliuk , Karen Westerman
- Applicant: Philippe Leboulch , Robert Pawliuk , Karen Westerman
- Applicant Address: US MA Cambridge
- Assignee: bluebird bio, Inc.
- Current Assignee: bluebird bio, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Jane E. Remillard, Esq.; James H. Velema, Esq.
- Main IPC: A01N63/00
- IPC: A01N63/00 ; C12N15/00 ; C07H21/04
Abstract:
The invention provides improved compositions and methods for achieving gene therapy in hematopoietic cells and hematopoietic precursor cells, including erythrocytes, erythroid progenitors, and embryonic stem cells. The invention further provides improved gene therapy methods for treating hematopoietic-related disorders. Retroviral gene therapy vectors that are optimized for erythroid specific expression and treatment of hemoglobinopathic conditions are disclosed.
Public/Granted literature
- US20060057725A1 Therapeutic retroviral vectors for gene therapy Public/Granted day:2006-03-16
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