Invention Grant
- Patent Title: Humanized anti-ghrelin antibodies
- Patent Title (中): 人源化抗Ghrelin抗体
-
Application No.: US12278419Application Date: 2007-02-21
-
Publication No.: US07901679B2Publication Date: 2011-03-08
- Inventor: David Matthew Marquis , Eric Michael Smith , Danise Rogers Subramaniam , Derrick Ryan Witcher
- Applicant: David Matthew Marquis , Eric Michael Smith , Danise Rogers Subramaniam , Derrick Ryan Witcher
- Applicant Address: US IN Indianapolis
- Assignee: Eli Lilly and Company
- Current Assignee: Eli Lilly and Company
- Current Assignee Address: US IN Indianapolis
- Agent Andrea M. Castetter
- International Application: PCT/US2007/062459 WO 20070221
- International Announcement: WO2007/101021 WO 20070907
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C12P21/08 ; A61K39/395 ; A61K39/00
Abstract:
Provided are humanized monoclonal antibodies, and antigen-binding portions thereof, which bind acylated and unacylated human ghrelin. Such antibodies are useful for neutralizing ghrelin activity and treating disorders in which ghrelin activity is detrimental, including obesity and related disorders, and various cancers.
Public/Granted literature
- US20090181018A1 HUMANIZED ANTI-GHRELIN ANTIBODIES Public/Granted day:2009-07-16
Information query
