Invention Grant
- Patent Title: Methods and compositions for determining the purity of chemically synthesized nucleic acids
- Patent Title (中): 用于测定化学合成核酸纯度的方法和组合物
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Application No.: US10190795Application Date: 2002-07-08
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Publication No.: US07901892B2Publication Date: 2011-03-08
- Inventor: Paul F. Agris , Christopher D. J. Pearce , Lloyd G. Mitchell
- Applicant: Paul F. Agris , Christopher D. J. Pearce , Lloyd G. Mitchell
- Applicant Address: US NC Raleigh
- Assignee: North Carolina State University
- Current Assignee: North Carolina State University
- Current Assignee Address: US NC Raleigh
- Agency: Myers Bigel Sibley & Sajovec, P.A.
- Main IPC: G01N33/53
- IPC: G01N33/53
Abstract:
This application describes an antibody that specifically binds to a synthetic oligomer (e.g., an oligonucleotide or oligopeptide) having a organic protecting group covalently bound thereto, which antibody does not bind to that synthetic oligomer when the organic protecting group is not covalently bound thereto. Methods of making and using such antibodies are also disclosed, along with cells for making such antibodies and articles carrying immobilized oligomers that can be used in assay procedures with such antibodies.
Public/Granted literature
- US20030044831A1 Methods and compositions for determining the purity of chemically synthesized nucleic acids Public/Granted day:2003-03-06
Information query
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