Invention Grant
US07901928B2 Acyltransferases for alteration of polyunsaturated fatty acids and oil content in oleaginous yeasts
有权
用于改变多不饱和脂肪酸的酰基转移酶和含油酵母中的油含量
- Patent Title: Acyltransferases for alteration of polyunsaturated fatty acids and oil content in oleaginous yeasts
- Patent Title (中): 用于改变多不饱和脂肪酸的酰基转移酶和含油酵母中的油含量
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Application No.: US12401650Application Date: 2009-03-11
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Publication No.: US07901928B2Publication Date: 2011-03-08
- Inventor: Narendra S. Yadav , Hongxiang Zhang
- Applicant: Narendra S. Yadav , Hongxiang Zhang
- Applicant Address: US DE Wilmington
- Assignee: E. I. du Pont de Nemours and Company
- Current Assignee: E. I. du Pont de Nemours and Company
- Current Assignee Address: US DE Wilmington
- Main IPC: C12N9/10
- IPC: C12N9/10 ; C12N1/20 ; C12N1/19 ; C12N1/16 ; C12P15/70 ; C12P7/64 ; C07H21/24
Abstract:
Two acyltransferases are provided, suitable for use in the manufacture of microbial oils enriched in omega fatty acids in oleaginous yeast (e.g., Yarrowia lipolytica). Specifically, the genes encoding phophatidylcholine-diacylglycerol acyltransferase (PDAT) and diacylglycerol acyltransferase (DGAT2) have been isolated from Y. lipolytica. These genes encode enzymes that participate in the terminal step in oil biosynthesis in yeast. Each is expected to play a key role in altering the quantity of polyunsaturated fatty acids produced in oils of oleaginous yeasts.
Public/Granted literature
- US20090269828A1 ACYLTRANSFERASES FOR ALTERATION OF POLYUNSATURATED FATTY ACIDS AND OIL CONTENT IN OLEAGINOUS YEASTS Public/Granted day:2009-10-29
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