Invention Grant
US07902156B2 Aprotinin polypeptides for transporting a compound across the blood-brain barrier
有权
用于将化合物转运穿过血脑屏障的抑肽酶多肽
- Patent Title: Aprotinin polypeptides for transporting a compound across the blood-brain barrier
- Patent Title (中): 用于将化合物转运穿过血脑屏障的抑肽酶多肽
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Application No.: US11884629Application Date: 2005-07-21
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Publication No.: US07902156B2Publication Date: 2011-03-08
- Inventor: Richard Béliveau , Michel Demeule , Christian Ché , Anthony Regina
- Applicant: Richard Béliveau , Michel Demeule , Christian Ché , Anthony Regina
- Applicant Address: CA Montreal
- Assignee: Angiochem Inc.
- Current Assignee: Angiochem Inc.
- Current Assignee Address: CA Montreal
- Agency: Clark Elbing LLP
- Agent Kristina Bieker-Brady
- International Application: PCT/CA2005/001158 WO 20050721
- International Announcement: WO2006/086870 WO 20060824
- Main IPC: A61K38/04
- IPC: A61K38/04 ; A61K38/16 ; A61K38/22
Abstract:
The invention relates to improvements in the field of drug delivery. More particularly, the invention relates to polypeptides derived from aprotinin and from aprotinin analogs as well as conjugates and pharmaceutical compositions comprising these polypeptides or conjugates. The present invention also relates to the use of these polypeptide for transporting a compound or drug across the blood-brain barrier of a mammal and in the treatment and diagnosis of neurological diseases.
Public/Granted literature
- US20080299039A1 Aprotinin Polypeptides for Transporting a Compound Across the Blood-Brain Barrier Public/Granted day:2008-12-04
Information query
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