Invention Grant
- Patent Title: ENA nucleic acid drugs modifying splicing in mRNA precursor
- Patent Title (中): ENA核酸药物修饰mRNA前体的剪接
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Application No.: US10536258Application Date: 2003-11-21
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Publication No.: US07902160B2Publication Date: 2011-03-08
- Inventor: Masafumi Matsuo , Yasuhiro Takeshima , Makoto Koizumi
- Applicant: Masafumi Matsuo , Yasuhiro Takeshima , Makoto Koizumi
- Applicant Address: JP Kobe-shi JP Kobe-shi JP Kobe-shi JP Hyogo
- Assignee: Masafumi Matsuo,Yasuhiro Takeshima,Nonprofit Organization Translational Research Organization of Duchenne Muscular Dystrophy,KNC Laboratories Co., Ltd.
- Current Assignee: Masafumi Matsuo,Yasuhiro Takeshima,Nonprofit Organization Translational Research Organization of Duchenne Muscular Dystrophy,KNC Laboratories Co., Ltd.
- Current Assignee Address: JP Kobe-shi JP Kobe-shi JP Kobe-shi JP Hyogo
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2002-340857 20021125; JP2003-204381 20030731
- International Application: PCT/JP03/14915 WO 20031121
- International Announcement: WO2004/048570 WO 20040610
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H21/04
Abstract:
Oligonucleotides having a nucleotide sequence complementary to nucleotide numbers such as 2571-2607, 2578-2592, 2571-2592, 2573-2592, 2578-2596, 2578-2601 or 2575-2592 of the dystrophin cDNA (Gene Bank accession No. NM_004006.1) and therapeutic agents for muscular dystrophy comprising such oligonucleotides.
Public/Granted literature
- US20070082861A1 Ena nucleic acid drugs modifying splicing in mrna precursor Public/Granted day:2007-04-12
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