Invention Grant
US07902185B2 Treatment of neurodegenerative diseases using proteasome modulators
失效
使用蛋白酶体调节剂治疗神经变性疾病
- Patent Title: Treatment of neurodegenerative diseases using proteasome modulators
- Patent Title (中): 使用蛋白酶体调节剂治疗神经变性疾病
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Application No.: US10453912Application Date: 2003-06-03
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Publication No.: US07902185B2Publication Date: 2011-03-08
- Inventor: Tennore M. Ramesh , Sean Scott
- Applicant: Tennore M. Ramesh , Sean Scott
- Applicant Address: US MA Cambridge
- Assignee: ALS Therapy Development Foundation, Inc.
- Current Assignee: ALS Therapy Development Foundation, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Nutter McClennen & Fish LLP
- Agent Thomas J. Engellenner
- Main IPC: A01N43/62
- IPC: A01N43/62 ; A01N43/04 ; A61K31/55 ; A61K31/70
Abstract:
Methods for modulating proteasome activity in a subject is provided. Proteasome activity is modulated by administering a therapeutically effective amount of proteasome modulating pharmacological agent to a subject. In a preferred embodiment, the proteasome modulating pharmacological agent is a protease inhibitor. In another aspect, a screening assay for detecting and identifying proteasome modulating pharmacological agents to modulate proteasome activity in a subject is also provided.
Public/Granted literature
- US20040138153A1 Treatment of neurodegenerative diseases using proteasome modulators Public/Granted day:2004-07-15
Information query
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