Invention Grant
- Patent Title: 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression
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Application No.: US12196516Application Date: 2008-08-22
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Publication No.: US07902187B2Publication Date: 2011-03-08
- Inventor: Irina Neagu , David Diller , Celia Kingsbury , Adolph C. Bohnstedt , Michael J. Ohlmeyer , Vidyadhar Paradkar , Nasrin Ansari
- Applicant: Irina Neagu , David Diller , Celia Kingsbury , Adolph C. Bohnstedt , Michael J. Ohlmeyer , Vidyadhar Paradkar , Nasrin Ansari
- Applicant Address: US NJ Madison
- Assignee: Wyeth LLC
- Current Assignee: Wyeth LLC
- Current Assignee Address: US NJ Madison
- Agent Ram W. Sabnis
- Main IPC: C07D473/32
- IPC: C07D473/32 ; C07D473/18 ; A61K31/52 ; A61K31/522 ; A61P37/06 ; A61P11/06 ; A61P35/02 ; C07D239/48 ; C07D239/50 ; C07D405/12 ; C07D405/14
Abstract:
The present invention provides novel purinones and purines useful for the prevention and treatment of autoimmune diseases, inflammatory disease, mast cell mediated disease and transplant rejection. The compounds are of the general formulae I and II shown below, in which Q is selected from the group consisting of CX and nitrogen; and A is chosen from the group consisting of H, (C1-C6) alkyl, heteroaryl, and aryl:
Public/Granted literature
- US20090069289A1 6-SUBSTITUTED 2-(BENZIMIDAZOLYL)PURINE AND PURINONE DERIVATIVES FOR IMMUNOSUPPRESSION Public/Granted day:2009-03-12
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