Invention Grant
US07902217B2 Indoles, 1H-indazoles, 1,2-benzisoxazoles, 1,2-benzoisothiazoles, and preparation and uses thereof
失效
吲哚，1H-吲唑，1,2-苯并异恶唑，1,2-苯并异噻唑及其制备和用途
- Patent Title: Indoles, 1H-indazoles, 1,2-benzisoxazoles, 1,2-benzoisothiazoles, and preparation and uses thereof
- Patent Title (中): 吲哚，1H-吲唑，1,2-苯并异恶唑，1,2-苯并异噻唑及其制备和用途
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Application No.: US12273039Application Date: 2008-11-18
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Publication No.: US07902217B2Publication Date: 2011-03-08
- Inventor: Wenge Xie , Brian Herbert , Jianguo Ma , Truc Minh Nguyen , Richard Schumacher , Carla Maria Gauss , Ashok Tehim
- Applicant: Wenge Xie , Brian Herbert , Jianguo Ma , Truc Minh Nguyen , Richard Schumacher , Carla Maria Gauss , Ashok Tehim
- Applicant Address: US NJ Montvale
- Assignee: Memory Pharmaceuticals Corporation
- Current Assignee: Memory Pharmaceuticals Corporation
- Current Assignee Address: US NJ Montvale
- Agency: Millen, White, Zelano & Branigan, P.C.
- Main IPC: A01N43/42
- IPC: A01N43/42 ; A61K31/44 ; C07D401/00 ; C07D405/00 ; C07D409/00 ; C07D221/02
Abstract:
The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nACh receptors), activation of nACh receptors, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (indazoles and benzothiazoles), which act as ligands for the α7 nACh receptor subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.
Public/Granted literature
- US20090118232A1 INDOLES, 1H-INDAZOLES, 1,2-BENZISOXAZOLES, 1,2-BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF Public/Granted day:2009-05-07
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