Invention Grant
US07902244B2 Method of preparing a pharmaceutical cream and minimizing imiquimod impurity formation (at least four months storage)
有权
制备药物霜剂并使咪喹莫特杂质形成最小化（至少四个月储存）的方法
- Patent Title: Method of preparing a pharmaceutical cream and minimizing imiquimod impurity formation (at least four months storage)
- Patent Title (中): 制备药物霜剂并使咪喹莫特杂质形成最小化（至少四个月储存）的方法
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Application No.: US12697434Application Date: 2010-02-01
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Publication No.: US07902244B2Publication Date: 2011-03-08
- Inventor: Alexis S. Statham , Robert J. Nelson
- Applicant: Alexis S. Statham , Robert J. Nelson
- Applicant Address: US MN St. Paul
- Assignee: 3M Innovative Properties Company
- Current Assignee: 3M Innovative Properties Company
- Current Assignee Address: US MN St. Paul
- Agency: Edwards Angell Palmer & Dodge LLP
- Agent Peter J. Manso
- Main IPC: A01N43/52
- IPC: A01N43/52 ; A01N43/42 ; A61K31/415 ; A61K31/44 ; C07D235/02
Abstract:
Pharmaceutical formulations and methods including an immune response modifier (IRM) compound and an oleic acid component are provided where stability is improved by using oleic acid have low polar impurities such as peroxides.
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