Invention Grant
- Patent Title: Porous photonic crystal with light scattering domains and methods of synthesis and use thereof
- Patent Title (中): 具有光散射域的多孔光子晶体及其合成和使用方法
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Application No.: US11665613Application Date: 2005-10-19
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Publication No.: US07903239B2Publication Date: 2011-03-08
- Inventor: Michael J. Sailor , Michael P. Schwartz , Sara Alvarez , Sangeeta Bhatia , Austin Derfus , Benjamin Migliori , Lin Chao , Yang Yang Li , Rebecca Campbell , Jason Dorvee , Ulla Camilla Rang
- Applicant: Michael J. Sailor , Michael P. Schwartz , Sara Alvarez , Sangeeta Bhatia , Austin Derfus , Benjamin Migliori , Lin Chao , Yang Yang Li , Rebecca Campbell , Jason Dorvee , Ulla Camilla Rang
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Greer, Burns & Crain Ltd.
- International Application: PCT/US2005/037572 WO 20051019
- International Announcement: WO2006/044957 WO 20060427
- Main IPC: G01N1/00
- IPC: G01N1/00
Abstract:
The invention includes sensors and sensing methods for determining cell morphology and/or chemical composition of an analyte. A porous substrate exhibiting a first optical signal is exposed to a target analyte and subsequently monitored for changes in the optical signal. More specifically, a photonic or porous substrate having a well-defined and highly tunable reflectivity or transmission spectrum, such as porous silicon (Si), porous alumina, porous Ge, porous GaAs, porous SiO2 and porous polymer, is used for example. A porous or photonic substrate is exposed to an analyte, such as a cell or other macromolecule, and changes in the scattered light are observed over time to determine cell morphology and/or chemical composition of the analyte using the substrate.
Public/Granted literature
- US20080212068A1 Porous Photonic Crystal with Light Scattering Domains and Methods of Synthesis and Use Thereof Public/Granted day:2008-09-04
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