A method and system for multi-user wireless communications between a sender and a receiver enables effective blocking of interference signals by other senders and improving the channel data rate. The receiver uses two or more receiving devices, such as antennas or smart antennas, to receive multiple wireless input signals. By performing a noise-transparent autocorrelation matching analysis on the multiple input signals, the receiver derives an anti-interference filter for interference-blocking action, without the need for information of the interfering and its transmission channel. In a multi-user environment, the noise-transparent autocorrelation matching analysis is implemented by the Autocorrelation Division Multiple Access (ADMA) system that includes the design and the implementation of ADMA code, the ADMA encoder, the ADMA algorithm and the ADMA decoder.