Invention Grant
- Patent Title: Programmable apparatus and method for optimizing and real time monitoring of gene transfection based on user configured arbitrary waveform pulsing train
- Patent Title (中): 基于用户配置的任意波形脉冲串优化和实时监测基因转染的可编程装置和方法
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Application No.: US11171451Application Date: 2005-07-01
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Publication No.: US07904172B2Publication Date: 2011-03-08
- Inventor: Oi Lian Kon , Mohamad Pauzi Bin Hussen , Steven Teck Boon Yap
- Applicant: Oi Lian Kon , Mohamad Pauzi Bin Hussen , Steven Teck Boon Yap
- Applicant Address: SG Singapore
- Assignee: Nanyang Polytechnic
- Current Assignee: Nanyang Polytechnic
- Current Assignee Address: SG Singapore
- Agency: Pyprus Pte Ltd
- Priority: SG200407948-9 20041228
- Main IPC: A61N1/30
- IPC: A61N1/30

Abstract:
The present invention provides an apparatus and a method for generating and applying an electric field according to a user configured arbitrary waveform pulsing train. A control module allows the user to input operation parameters and configure the arbitrary waveform pulsing train for the electroporation process. A micro-controller unit coupled to the control module controls an arbitrary waveform generator unit and a customized power module. During the electroporation process, the arbitrary waveform generator unit produces the arbitrary waveform pulsing train that is amplified by the customized power module. The customized power module is coupled to at least two electrodes, wherein the at least two electrodes will produce an electric field across a target media.
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