Invention Grant
- Patent Title: Computer software to assist in identifying SNPS with microarrays
- Patent Title (中): 计算机软件帮助识别SNPS与微阵列
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Application No.: US11043294Application Date: 2005-01-26
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Publication No.: US07904250B2Publication Date: 2011-03-08
- Inventor: Michael Molla , Todd Richmond , Steven Smith , Thomas Albert
- Applicant: Michael Molla , Todd Richmond , Steven Smith , Thomas Albert
- Applicant Address: US DE Wilmington
- Assignee: Roche Nimblegen, Inc.
- Current Assignee: Roche Nimblegen, Inc.
- Current Assignee Address: US DE Wilmington
- Agency: Quarles & Brady LLP
- Main IPC: G01N33/50
- IPC: G01N33/50
Abstract:
The present invention is a method to assist in the identification of single nucleotide polymorphisms (SNP) from microarray hybridization data. Data from hybridization protocols run on microarrays often have variations in the data resulting from variations in hybridization conditions and efficiencies and variations in optical intensities. An algorithm is described to screen the results to identify those data points most likely to be real SNPs as opposed to variations in the hybridization or sensing data.
Public/Granted literature
- US20060014164A1 Computer software to assist in identifying SNPS with microarrays Public/Granted day:2006-01-19
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