An actuator control system is disclosed. The actuator control system may have a pump and at least one actuator. The actuator control system may further have an actuator valve configured to control the at least one actuator. The actuator control system may also have a pump pressure sensor configured to determine a pump pressure value and a load pressure sensor configure to determine a load pressure value. The actuator control system may additionally have a controller configured to receive the pump pressure value and the load pressure value. The controller may further be configured to compare the pump pressure value and the load pressure value, and selectively implement a primary control strategy and a secondary control strategy based on the comparison.