Invention Grant
- Patent Title: Ligands to radiation-induced molecules
- Patent Title (中): 对辐射诱导分子的配体
-
Application No.: US11183325Application Date: 2005-07-15
-
Publication No.: US07906102B2Publication Date: 2011-03-15
- Inventor: Dennis E. Hallahan , Shimian Qu , Zhaozhong Han
- Applicant: Dennis E. Hallahan , Shimian Qu , Zhaozhong Han
- Applicant Address: US TN Nashville
- Assignee: Vanderbilt University
- Current Assignee: Vanderbilt University
- Current Assignee Address: US TN Nashville
- Main IPC: A61K51/00
- IPC: A61K51/00 ; A61M36/14

Abstract:
A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands.
Public/Granted literature
- US20060104898A1 Ligands to radiation-induced molecules Public/Granted day:2006-05-18
Information query