Invention Grant
US07906635B2 Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of ovarian cancer
有权
核苷酸和氨基酸序列,以及其用于诊断卵巢癌的测定和方法
- Patent Title: Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of ovarian cancer
- Patent Title (中): 核苷酸和氨基酸序列,以及其用于诊断卵巢癌的测定和方法
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Application No.: US12354641Application Date: 2009-01-15
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Publication No.: US07906635B2Publication Date: 2011-03-15
- Inventor: Gad S. Cojocaru , Sarah Pollock , Zurit Levine , Alexander Diber , Guy Kol , Amir Toporik , Rotem Sorek , Dvir Dahary , Michal Ayalon-Soffer , Pinchas Akiva , Amit Novik , Yossi Cohen , Osnat Sella-Tavor , Shira Walach , Shirley Sameah-Greenwald , Ronen Shemesh , Maxim Shklar
- Applicant: Gad S. Cojocaru , Sarah Pollock , Zurit Levine , Alexander Diber , Guy Kol , Amir Toporik , Rotem Sorek , Dvir Dahary , Michal Ayalon-Soffer , Pinchas Akiva , Amit Novik , Yossi Cohen , Osnat Sella-Tavor , Shira Walach , Shirley Sameah-Greenwald , Ronen Shemesh , Maxim Shklar
- Applicant Address: IL Tel Aviv
- Assignee: Compugen Ltd.
- Current Assignee: Compugen Ltd.
- Current Assignee Address: IL Tel Aviv
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent Ivor R. Elrifi; David E. Johnson, Esq.
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C12Q1/68

Abstract:
Novel markers for ovarian cancer that are both sensitive and accurate. These markers are overexpressed and/or differentially expressed in ovarian cancer specifically, as opposed to normal ovarian tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis, in ovarian cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between ovarian cancer and non-cancerous states.
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