A unified open loop single-user/multiple-user multiple-input-multiple-output (MIMO) system and method are disclosed. The system and method operate without use of channel state information feedback. Instead, the method utilizes channel quality indicator feedback to schedule users to spatial resource blocks. Both symmetric multi-user MIMO schemes (like 2×2 and 4×4) and asymmetric multi-user MIMO schemes are considered. CQI feedback and reduction proposals are also introduced. The method may be used in a proposed network topology.