Invention Grant
US07917303B2 Method for identifying combinations of motifs that do not mutate simultaneously in a set of viral polypeptide sequences comprising a putative drug binding site
有权
用于鉴定在一组病毒多肽序列中同时突变的基序组合的方法，所述病毒多肽序列包含推定的药物结合位点
- Patent Title: Method for identifying combinations of motifs that do not mutate simultaneously in a set of viral polypeptide sequences comprising a putative drug binding site
- Patent Title (中): 用于鉴定在一组病毒多肽序列中同时突变的基序组合的方法，所述病毒多肽序列包含推定的药物结合位点
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Application No.: US11480014Application Date: 2006-06-30
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Publication No.: US07917303B2Publication Date: 2011-03-29
- Inventor: Anne Vanet , Michaela Muller-Trutwin , Thomas Valère , Sophie Brouillet , Emmanuelle Ollivier , Laurent Marsan
- Applicant: Anne Vanet , Michaela Muller-Trutwin , Thomas Valère , Sophie Brouillet , Emmanuelle Ollivier , Laurent Marsan
- Applicant Address: FR
- Assignee: Centre National de la Recherche Scientifique—CNRS
- Current Assignee: Centre National de la Recherche Scientifique—CNRS
- Current Assignee Address: FR
- Agency: DLA Piper LLP (US)
- Priority: FR0107808 20010614
- Main IPC: G01N33/48
- IPC: G01N33/48
Abstract:
Methods for identifying a motif or a combination of motifs having a Boolean state of predetermined mutations in a set of sequences including a) aligning a set of sequences of ordered motifs represented by a single-character code, b) comparing a reference sequence with the set of sequences aligned in step (a), c) identifying motifs not having mutated simultaneously and/or motifs having mutated simultaneously at least once on at least one sequence of the set and not having mutated on another sequence of the set.
Public/Granted literature
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