A power supply system suitable for being located in a computer is provided. The system includes a first voltage regulator module (VRM), a second VRM, a first switch unit, and a second switch unit. The first VRM is used to supply a first power. The second VRM is used to supply a second power. The first switch unit is used for controlling the first power to be transmitted to a first central processing unit (CPU) socket by a first power supply path or to a second CPU socket by a second power supply path. The second switch unit is used for controlling the second power to be transmitted to the first CPU socket by the third power supply path or to the second CPU socket by the fourth power supply path.