In the invention, a run-flat tire including a pair of bead portions having an annular first bead, sidewall portions respectively extending to an outer side in a tire diametrical direction from the bead portions, reinforce rubber layers arranged in the sidewall portions, a tread portion connecting outer peripheral side ends of the sidewall portions via shoulder portions, wherein the run-flat tire includes an annular inflating portion provided on the outside in a tire width direction of the bead portion arranged on the outside of the vehicle, and having an inner circumferential side face opposing to an outer circumferential curved side face of a rim flange when a regular rim is fixed; and an annular second bead arranged at the annular inflating portion, wherein the reinforce rubber layer arranged on the outside of the vehicle has a rubber hardness of 60 to 82 degree, the reinforce rubber layer arranged on the inside of the vehicle has a rubber hardness of 65 to 90 degree, and the reinforce rubber layer arranged on the inside of the vehicle has the rubber hardness which is equal to or more than that on the outside of the vehicle, and has a maximum thickness which is larger than that on the outside of the vehicle by at least 0.5 mm.