A composition for destruction of unused or expired medicines comprised of: an acidic solvent; a dishwashing liquid; and activated carbon. The acidic solvent can be distilled vinegar, lemon juice, hydrochloric acid, diluted hydrochloric acid, acetic acid, diluted acetic acid, bleach, ammonia, alcohol, and combinations thereof, the dishwashing liquid includes at least one anionic surfactant, at least one nonionic surfactant, and cocinin, and the activated carbon is selected can be powdered activated carbon or granulated activated carbon, typically with a surface area of at least approximately 500 square meters per gram. The composition can further include fragrance and/or coloring. The components of the composition can also be sold individually or one or more components can be sold together with a container.