Invention Grant
US07919093B2 Roles for dual endothelin-1/angiotensin II receptor (Dear) in hypertension and angiogenesis
有权
双重内皮素-1 /血管紧张素II受体(Dear)在高血压和血管生成中的作用
- Patent Title: Roles for dual endothelin-1/angiotensin II receptor (Dear) in hypertension and angiogenesis
- Patent Title (中): 双重内皮素-1 /血管紧张素II受体(Dear)在高血压和血管生成中的作用
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Application No.: US11667713Application Date: 2005-11-15
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Publication No.: US07919093B2Publication Date: 2011-04-05
- Inventor: Victoria L. M. Herrera , Nelson Ruiz-Opazo
- Applicant: Victoria L. M. Herrera , Nelson Ruiz-Opazo
- Applicant Address: US MA Boston
- Assignee: Trustees of Boston University
- Current Assignee: Trustees of Boston University
- Current Assignee Address: US MA Boston
- Agency: Nixon Peabody LLP
- International Application: PCT/US2005/041594 WO 20051115
- International Announcement: WO2006/055665 WO 20060526
- Main IPC: C07K16/28
- IPC: C07K16/28

Abstract:
The present application is directed to the identification of mutations and/or polymorphisms in the Dual Endothelin-1/Angiotensin II Receptor (Dear) that indicate susceptibility to, or show current affliction with, hypertension. Additionally, the present invention discloses methods for the modulation of angiogenesis via the regulation of Dear.
Public/Granted literature
- US20090028852A1 Roles For Dual Endothelin-1/Angiotensin II Receptor (DEAR) In Hypertension and Angiogenesis Public/Granted day:2009-01-29
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