Invention Grant
- Patent Title: Anti-IL-6 monoclonal antibodies
- Patent Title (中): 抗IL-6单克隆抗体
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Application No.: US11882751Application Date: 2007-08-03
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Publication No.: US07919095B2Publication Date: 2011-04-05
- Inventor: Ernest S. Smith , Wei Wang
- Applicant: Ernest S. Smith , Wei Wang
- Applicant Address: US NY Rochester
- Assignee: Vaccinex, Inc.
- Current Assignee: Vaccinex, Inc.
- Current Assignee Address: US NY Rochester
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/24
Abstract:
The present invention provides novel monoclonal antibodies that bind specifically to IL-6. The antibodies of the invention comprise a variable heavy chain (VH) region selected from any of the VH regions disclosed herein as well as amino acid variants thereof, and/or a variable light chain (VL) region selected from any of the VL regions disclosed herein as well as amino acid variants thereof. The invention also provides methods of treating diseases and disorders associated with IL-6 expression and/or activity.
Public/Granted literature
- US20080075726A1 Anti-IL-6 monoclonal antibodies and uses thereof Public/Granted day:2008-03-27
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