Invention Grant
US07919117B2 Transdermal delivery of (R)-3,3-diphenylpropylamin-monoestern
有权
透皮递送(R)-3,3-二苯基丙基胺 - 单一
- Patent Title: Transdermal delivery of (R)-3,3-diphenylpropylamin-monoestern
- Patent Title (中): 透皮递送(R)-3,3-二苯基丙基胺 - 单一
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Application No.: US12417405Application Date: 2009-04-02
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Publication No.: US07919117B2Publication Date: 2011-04-05
- Inventor: Armin Breitenbach , Claus Meese , Hans-Michael Wolff , Roland Drews
- Applicant: Armin Breitenbach , Claus Meese , Hans-Michael Wolff , Roland Drews
- Applicant Address: DE Monheim
- Assignee: UCB Pharma GmbH
- Current Assignee: UCB Pharma GmbH
- Current Assignee Address: DE Monheim
- Agency: Kenyon & Kenyon LLP
- Priority: DE10315878 20030408
- Main IPC: A61K9/14
- IPC: A61K9/14

Abstract:
The invention relates to a device for transdermally administering a compound of formula (I), wherein A represents hydrogen or deuterium, R represents a group selected among C1-4alkyl, C3-10cycloalkyl, or phenyl, each of which can be substituted by C1-3alkoxy, fluoride, chlorine, bromine, iodine, nitro, amino, hydroxy, oxo, mercapto, or deuterium, the C atom marked by * (asterisk) being provided in the R configuration. The invention is characterized in that the compound of general formula (I) is provided in a polymer matrix and is released at a dose of 0.5 to 20 mg per day through human skin. The invention further relates to the use of said compounds of formula (I) for producing transdermal medicaments.
Public/Granted literature
- US20090274761A1 TRANSDERMAL DELIVERY OF (R)-3,3-DIPHENYLPROPYLAMIN-MONOESTERN Public/Granted day:2009-11-05
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