Invention Grant
US07919118B2 Spacer moiety for poly (ethylene glycol) modified peptide based compounds
有权
用于聚（乙二醇）修饰的肽基化合物的间隔部分
- Patent Title: Spacer moiety for poly (ethylene glycol) modified peptide based compounds
- Patent Title (中): 用于聚（乙二醇）修饰的肽基化合物的间隔部分
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Application No.: US10555860Application Date: 2004-05-12
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Publication No.: US07919118B2Publication Date: 2011-04-05
- Inventor: Christopher P. Holmes , Qun Yin , David Tumelty
- Applicant: Christopher P. Holmes , Qun Yin , David Tumelty
- Assignee: Affymax, Inc.
- Current Assignee: Affymax, Inc.
- Agency: Fish & Richardson P.C.
- International Application: PCT/US2004/014887 WO 20040512
- International Announcement: WO2004/100997 WO 20041125
- Main IPC: A61K9/00
- IPC: A61K9/00 ; A61K38/00 ; C07K2/00
Abstract:
The present invention relates to a compound comprising a peptide moiety, a spacer moiety and a water-soluble polymer moiety such as a poly(ethylene glycol) moiety. The spacer moiety is between the peptide moiety and the water-soluble polymer moiety. The spacer moiety has the structure: —NH—(CH2)α—[O—(CH2)β]γ—Oδ—(CH2)ε—Y— wherein α, β, γ, δ, and ε are each integers whose values are independently selected.
Public/Granted literature
- US20070032408A1 Novel spacer moiety for poly (ethylene glycol) modified peptide based compounds Public/Granted day:2007-02-08
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