Invention Grant
- Patent Title: Methods and compositions for determining the efficacy of a treatment for ankylosing spondylitis using biomarkers
- Patent Title (中): 使用生物标志物测定强直性脊柱炎治疗功效的方法和组合物
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Application No.: US11591241Application Date: 2006-10-31
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Publication No.: US07919264B2Publication Date: 2011-04-05
- Inventor: Walter P. Maksymowych , Robert L. Wong
- Applicant: Walter P. Maksymowych , Robert L. Wong
- Applicant Address: BM Hamilton
- Assignee: Abbott Biotechnology Ltd.
- Current Assignee: Abbott Biotechnology Ltd.
- Current Assignee Address: BM Hamilton
- Agency: McCarter & English, LLP
- Agent Cristin Howley Cowles; Deborah L. Nagle
- Main IPC: C12Q1/00
- IPC: C12Q1/00 ; C12Q1/37 ; G01N33/573 ; G01N33/68
Abstract:
The invention provides a method for determining the efficacy of a TNFα inhibitor, such as a TNFα antibody, or an antigen-binding portion thereof, for treating ankylosing spondylitis (AS), using a collagen degradation biomarker and/or a synovitis biomarker.
Public/Granted literature
- US20070172897A1 Methods and compositions for diagnosing ankylosing spondylitis using biomarkers Public/Granted day:2007-07-26
Information query
