Invention Grant
- Patent Title: Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression
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Application No.: US12218035Application Date: 2008-07-10
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Publication No.: US07919313B2Publication Date: 2011-04-05
- Inventor: Trevor Collingwood , Gregory J. Cost
- Applicant: Trevor Collingwood , Gregory J. Cost
- Applicant Address: US CA Richmond
- Assignee: Sangamo Biosciences, Inc.
- Current Assignee: Sangamo Biosciences, Inc.
- Current Assignee Address: US CA Richmond
- Agency: Robins & Pasternak LLP
- Agent Dahna S. Pasternak
- Main IPC: C07H17/00
- IPC: C07H17/00 ; C07K14/00
Abstract:
Disclosed herein are methods and compositions for inactivating a FUT8 gene, using fusion proteins comprising a zinc finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins.
Public/Granted literature
- US20090042250A1 Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression Public/Granted day:2009-02-12
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